Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Almost all of China’s gold goes to meet domestic demand, since companies are not allowed to export gold.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Final predictions: Weak economic growth will continue into 2010. By spring, the Obama White House will be forced to the political center and U.S. businesses will finally believe in a modest recovery.
Industrial production rose 6.1 per cent year on year in October, according to China’s National Bureau of Statistics, unchanged from September’s level and just below a median forecast from economists of 6.2 per cent.
Trends and targets in antiviral phototherapy
New Year should be a time of banked-up fines, the scent of flowers and wine, good talk, good memories and loyalties renewed. But if all else is lacking - love will do.
The report by iResearch Consulting Group and Sina Weibo, China's most popular microblogging platform, was released at a forum in Shanghai, co-organized by Weibo and telecom giant Huawei .
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
伦敦商学院的MBA课程位列欧洲第一，与美国哥伦比亚商学院(Columbia Business School)合办的EMBA课程位列第三，管理硕士课程首次参与排名就跻身前10名。参与管理硕士课程排名是伦敦商学院夺得欧洲榜首的关键因素。
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Although Chinese domestic suppliers have expanded their market share to 32.7% in 2016, the trend was reversed in 2017, as their share shrank to 26.8%, said Qu Daokui, president of China Robot Industry Alliance.
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
While there is a still a way to go to ensure the LGBT community has the same rights as sexual couples, the world has moved on significantly in recent years. In fact, gay marriage is now legal for 60% of Americans. What about the other 40%, you ask? The List Love really believes the rest of the United States, and many other countries across the world – we’re talking to you, Russia! -will catch up soon.
It was the lesson of the UK general election and it's the big 'takeaway' from Cannes too: prediction is a mug's game. All week the chatter was that Todd Haynes' lesbian love story Carol was set to collect the Palme d'Or – or that Holocaust drama Son of Saul from first-time director László Nemes would triumph. In the last few days a consensus began to form around The Assassin from Taiwanese director Hou Hsiao-Hsien; according to British bookmakers, The Lobster was the one to beat. But when Jacques Audiard's Dheepan was announced as the winner, the response was a collective “really?” For all the pundits, critics' panels, insider gossip, statistics and God knows what else, few had picked it. Oh well: c'est la vie.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Transforming and upgrading the real economy through innovation
Apple's brand value rose 5 percent from a year ago to $178 billion and Google's brand value was up 11 percent from a year ago to $133 billion, according to the report.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
The Handmaid's Tale
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
2014年出现了这么多大有前途的新剧：《真探》(True Detective)、《荣耀之女》(The Honorable Woman)、《冰血暴》(Fargo)、《婚外情》(The Affair)、《奥丽芙·基特里奇》(Olive Kitteridge)和《硅谷》(Silicon Valley)等。有些老剧仍在坚持，或者莫名其妙地重振雄风，或者在被砍后再次回归，最显眼的是丽莎·库卓(Lisa Kudrow)主演的HBO喜剧《归来记》(The Comeback)，它在2005年播出一季后被砍，今年11月回归。
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
You might want to hope that people shared these articles as a joke. I want to hope that. But we can’t: the analysis points to a recent BuzzFeed and Ipsos Public Affairs poll which found that 75 percent of Americans (84 percent of Republicans and 71 percent of Democrats) were easily tricked by fake headlines. What a fantastic year for fact-checking and rational thought and Mark Zuckerberg’s self-awareness.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
（传说中的中心对称！！！！）不过Illuminati的对称文已经遗失，下面的对称文是Dan Brown在写《天使与魔鬼》的时候找朋友设计的。 就《天使与魔鬼》一书描述，尽管很多人怀疑该组织的真实性，但光照派的确存在，至今如此，并且已经渗入了当今各个领域，尤其是很多共济会成员都在其中。
Antiviral drug discovery: broad-spectrum drugs from nature
Influenza neuraminidase: A druggable target for natural products
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
The 24K pizza is available at Industry Kitchen, an eatery in New York City's South Street Seaport, for a whopping $2,000 and, as the name would suggest, is noted for being covered in flakes of 24-karat gold.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Over 90 percent of them attended schools in English-speaking countries, such as the US, the UK and Australia, and over 70 percent pursue at least a bachelor's degree, according to the MOE.
Sliced into eight pieces, the pizza works out to $250 per slice, meaning it costs roughly $50 per bite.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
"It is a truly a global phenomenon in which people, due to lack of opportunities, have to leave their families behind to provide for them," said Pedro De Vasconcelos, IFAD policy advisor and author of the report.
LONDON — Since its inception in 2002, the Saturday Profile has aimed to bring to readers of The New York Times people around the world they probably have never heard of, but who have led interesting lives and done extraordinary things, or perhaps recently gone through a remarkable experience.
'For what is really exceptional, not seen on the market, there are really clients looking for such investments,'
The unexpected drop in 2013 came in spite of new policies--such as the city's 72- hour visa waiver for transit passengers--that were introduced in an attempt to nurture China's tourism industry.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Except your Watson, he thinks it's hot.
Inhibition of SARS coronavirus helicase by bismuth complexes
Surveys indicate that a majority of women suffer or have suffered gender prejudice when looking for a job, because employers do not want to grant maternity leave. To avoid possible gender discrimination from employers as a result of their entitlement to maternity leave and increase their employment competitiveness, some female job seekers have reportedly chosen to get married and have their children before graduating from universities.
Beijing targets consumer prices inflation at 3.5 per cent, but weakening growth is keeping prices benign.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
“We weren’t looking to throw the bums out, as they might say about an election. We were just really impressed with a flood of new powertrains, ” says Drew Winter, WardsAuto World Editor-in-Chief. “What was great yesterday might be less impressive tomorrow because engine technology is changing so rapidly.”
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The latest government figures were a big jump from data in mid-December, when1,200 people were said to have left or are seeking to leave to battle alongside jihadists.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Cristiano Ronaldo, the superstar footballer who earned 61 million pound last year, usurped long-term leader Floyd Mayweather Jnr into first place. The retired boxer, who fought just once in the last 12 months, earned pound 30 million.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
5. Repeats & highlights are as good as the main match, so am gonna watch them.
The new Spider-Man reboot is the best yet, and it's mostly because the movie is funny. Like, Breakfast Club meets Ferris Bueller's Day Off meets Freaks and Geeks funny.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Its selection of Mr Trump neither accords with the votes cast in the election nor reflects judgment of the candidate’s merits, as desired by Alexander Hamilton.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
In Pakistani Fray, Maryam Sharif Is on the Edge of Power, or Prison
Although the timing is purely a coincidence, it can’t hurt that Magento’s first product manager, Tim Schulz, just joined Bigcommerce as senior vice president of product management. Most recently a strategic partnership and business development executive for Google for services such as Shopping Express and Wallet, Schulz will be sharply focused on ensuring Bigcommerce offers an integrated experience that better straddles the e-commerce and physical retail worlds. “Consumers just want a seamless experience,” he said.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The government also needs to adopt the Internet Plus governance to ensure that government services will be more easily accessible for our people.
6. Smart refrigerator
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The programme has enabled me to take a quantum leap in my career and prepared me to take on a strategic C-level [chief-level] role right after graduation, said another alumnus.
That even at a lower profit margin (say, 40%) and a 1/3 cannibalization rate (i.e. customers buy one third fewer full-priced iPhones), the cheaper iPhone would increase Apple'srevenue and gross profits (see her spreadsheet above).
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
《余秀华：从普通农妇到著名诗人》(A Chinese Poet’s Unusual Path From Isolated Farm Life to Celebrity)
I'm only a child yet I know we are all in this together and should act as one single world towards one single goal. 我身为小孩都知道，我们在地球的母亲怀中都是孩子。我们应该为了相同的目的进行相同的行动！
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Taylor Swift and Katy Perry opted for bedazzled5 dresses in very different styles. Taylor went for a more old Hollywood, glamorous Grecian style that exposed her back and statuesque6 figure, while Katy rocked a shorter, spunkier look that exposed a little of everything.
4.Virtual Assistant: 17.6 percent increase
A modular microarray imaging system for highly specific COVID-19 antibody testing
2013 Rank: 2
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
The computer is a very powerful machine built with ARM processors, the kind low-power processors that run smartphones and tablets. These servers allow more computing power o be packed into a smaller space. And that has big implications for building green-but-powerful data centers."I think of myself as an entrepreneur besides just being an electrical engineer. I believe what I'm doing can have a major effective on the world," Sohmers said.He dropped out of high school to join Peter Thiel's controversial startup accelerator, the 20 Under 20 Thiel Fellowship. Thiel, the former PayPal CEO and famous Silicon Valley venture capitalist known for his early investment in Facebook, is a libertarian who has often spoken out about the absurd cost of college these days.So in 2011, he started a program that encourages kids to start companies instead of going to college. It gives them $100,000 in seed money and access to some of the Valley's greatest technologists as mentors.Sohmers is an electrical engineering prodigy who at age 13 started working at the research lab at MIT. That's where he met his co-founder and CTO, Keville, he said.
Last year was the hottest on earth since record-keeping began in 1880, scientists reported on Friday, underscoring warnings about the risks of runaway greenhouse gas emissions and undermining claims by climate change contrarians that global warming had somehow stopped.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
幸好这类单曲只是《名誉》这张专辑的一部分。在《Dress》（《连衣裙》）这首歌中，她沉醉于令人激动的新恋情里；在《New Year’s Day》（《新年》）这首歌中，她试着弄明白聚会结束后她还拥有什么。
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
The crown passed from the Plantagenet dynasty to the Tudor monarchs who painted Richard as a deformed villain who stopped at nothing in his quest for power, even murdering his two young nephews -- the so-called Princes in the Tower -- to secure the throne.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
7. WordPress CMS
尽管在2008 年9 月被任命为美国时代华纳集团旗下《型时代》杂志总编辑的阿里尔·福克斯曼是榜单新人，很少参加电视节目，但他的时尚总监哈尔·鲁本斯坦现在是美国“一生” 女性频道《幻彩魔刷：寻找下一个化妆大师》节目的评委。福克斯曼的刊物在广告页数上领先，据称在2009 年上半年总计超过1000 页。
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
12. Zoho CRM
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
12. Zoho CRM
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
In addition to WeChat's core private and group messaging functions, users can also find new contacts by using the application's Drift Bottle function, where a user records a message and sends it out to see in a virtual bottle for a stranger to pick up and respond. Its Look Around function, similar to some mobile dating applications, allows users to browse the profiles of other users who are in close proximity. It also has a function called Moments that allows users to share photo albums publicly with groups of contacts, much like photo-sharing application Instagram.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
People walk in the rain along the swollen Potomac River in the Georgetown neighborhood of Washington, DC, on Tuesday.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Alternative fuels: For the first time since diesel-powered cars from Europe started arriving here in the 1950s, old first-person accounts about the joys of driving a diesel fall off to near zero. They are replaced by new first-person accounts about the joys of driving cars with ridiculously high horsepower like the 580-hp Chevrolet Camaro ZL1 and Dodge’s Challenger SRT Hellfire with 707 hp. Elsewhere: fuel-cell cars with their longer cruising range move center-stage, stealing the limelight from battery-powered cars.
Anti-HIV drug repurposing against SARS-CoV-2
超过35万的欧洲玩家（还有一些北美和亚洲玩家）带着朝圣般的心情，赶赴人口刚过100万的德国科隆市，参加一年一度的游戏盛会。美国动视（Activision）在展览中首次公布了Sledgehammer Games工作室的多人游戏《使命召唤：高级战争》（Call of Duty: Advanced Warfare），现场玩家亲身体验了这款将于11月3日正式发布的游戏。
Lots of managers recalled extreme etiquette errors. The applicant
“Welcome to Me” (Shira Piven)
Length-scale dependence of protein hydration-shell density
Dachis says: The news just keeps getting worse for Mitsubishi. Low sales triggered a decision to pull out of the European market and if the levels of negative discussion are any indicator, 2013 doesn’t look to be any better.
Mr Draghi hit back the day after the December vote, saying that there was no “limit” to what eurozone policymakers could do to return inflation to its target.
She told The Telegraph: 'I don't feel that normal any more because I get recognised, even when I'm just trying to have fun or going to get ice cream with my friends.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Notably, the domain name for the top fake news story of the year is “abcnews.com.co.” In a November interview with The Verge, Professor Nicole A. Cooke of the University of Illinois’ School of Information Sciences cited the slight modification of familiar domains as a particularly dangerous and common tactic for fake news sites. They make the source look reputable at first glance. The man who operates abcnews.com.co told The Washington Post that he believes his websites were a key factor in the election of Donald Trump.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
联系方式:Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com
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总部位于芝加哥的竞争对手科尔尼(AT Kearney)也在为领导层变动做准备，计划于2018年第一季度投票决定接替约翰奥利格(Johan Aurik)的人选。管理合伙人最多担任两个任期，而奥利格已经期满。预计他的继任者将专注于让科尔尼做大，摆脱中等规模参与者之列。